You may need clopidogrel to prevent future issues if you had a heart attack, stroke or certain types of heart surgery. When clots form inside blood vessels, they can block the flow of blood to your heart, lungs, brain, or anywhere else in your body. This can result in serious conditions such as heart attack and stroke. Plavix works to prevent these conditions by helping prevent blood clots from forming. It belongs to a class of drugs called platelet inhibitors. By inhibiting (blocking) the activity of platelets, drugs like Plavix help to prevent your body from making too many clots.
Serious bleeding warning
- The sections above describe the usual dosages provided by the drug’s manufacturer.
- The expiration date helps guarantee that the medication is effective during this time.
- However, animal studies have found that Plavix crosses into breast milk.
- A generic drug is an exact copy of the active drug in a brand-name medication.
They can check to see whether you’re having serious bleeding and recommend if you need medical treatment. A skin rash may be a symptom of an allergic reaction to the drug. (See the section above called “Allergic reaction” for more details.) However, skin rashes can also https://rehabliving.net/signs-and-symptoms-of-spice-abuse/ be a symptom of a dangerous condition called thrombotic thrombocytopenic purpura (TTP). For more information on the possible side effects of Plavix, talk with your doctor or pharmacist. They can give you tips on how to deal with any side effects that may be bothersome.
Usual Adult Dose for Myocardial Infarction
This Medication Guide does not take the place of talking with your doctor about your medical condition or your treatment. After single and repeated oral doses of 75 mg per day, clopidogrel is rapidly https://soberhome.net/alcohol-misconceptions-can-alcoholism-be-cured/ absorbed. Absorption is at least 50%, based on urinary excretion of clopidogrel metabolites. Clopidogrel use during labor or delivery will increase the risk of maternal bleeding and hemorrhage.
What Is Considered Stroke-Level High Blood Pressure?
Deaths not easily attributable to nonvascular causes were all classified as vascular. Clopidogrel is an inhibitor of platelet activation and aggregation through the irreversible binding of its active metabolite to the P2Y12 class of ADP receptors on platelets. In COMMIT, approximately 58% of the patients treated with Plavix were 60 years and older, 26% of whom were 70 years and older. 75 mg once daily orally without a loading dose [see CLINICAL PHARMACOLOGY and Clinical Studies].
Treatment & Diagnosis
Plavix can interact with certain other drugs that are metabolized (processed) by the same enzymes (proteins) in your liver. For example, proton pump inhibitors are a class of drugs that are metabolized by the enzymes that break down Plavix. Taking these drugs with Plavix can make Plavix less effective for you. The use of Plavix and Effient has been directly compared in studies. In one clinical study, people who’d had a recent ACS event and were scheduled to receive PCI were given either Plavix and aspirin or Effient and aspirin.
What Does a Blood Clot Feel Like?
Be sure to tell your doctor if you experience fatigue during clopidogrel treatment. They can help determine the cause of the symptom and recommend ways to manage it. Clopidogrel can interact with several other medications. It can also interact with certain supplements as well as certain foods.
Researchers followed the people to see if they would have a stroke, heart attack, or cardiovascular-related death. In comparison, 4.8% of people taking aspirin had a stroke. Plavix is https://sober-home.org/a-review-on-alcohol-from-the-central-action/ used to help prevent blood clots from forming in your body. If you’re taking Plavix, you were probably started on the drug because you had an increased risk of having blood clots.
Using more than the recommended dosage of Plavix can lead to serious side effects. If you and your doctor determine that Plavix is safe and effective for you, you’ll likely take it long term. One exception to this is that your doctor may recommend that you avoid consuming grapefruit and grapefruit juice while you’re taking Plavix. For more information, see the “Plavix interactions” section above.
The results of animal studies showed that clopidogrel had no effect on the fertility of male or female rats. Clopidogrel may be available through a mail-order pharmacy. Using this service may help lower the drug’s cost and allow you to get your medication without leaving home. Your doctor can provide you with details about these interactions with clopidogrel.
It is also important information to carry with you in case of emergencies. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. Because of the risk of bleeding, you may need to stop taking clopidogrel for a short time before having surgery or dental work. Clopidogrel slows the blood’s clotting action by making platelets less sticky.